4-[6-(tributylstannyl)-2-pyridinyl]morpholine

4-[6-(tributylstannyl)-2-pyridinyl]morpholine - Names and Identifiers

Name	4-[6-(tributylstannanyl)pyridin-2-yl]morpholine
Synonyms	LogP 4-[6-(Tributylstannyl)pyridin-2-yl]morpholine 4-[6-(tributylstannyl)-2-pyridinyl]morpholine 4-[6-(TRIBUTYLSTANNYL)-2-PYRIDINYL]MORPHOLINE 4-[6-(tributylstannanyl)pyridin-2-yl]morpholine Morpholine, 4-[6-(tributylstannyl)-2-pyridinyl]-
CAS	869901-24-6
InChI	InChI=1/C9H11N2O.3C4H9.Sn/c1-2-4-10-9(3-1)11-5-7-12-8-6-11;31-3-4-2;/h1-3H,5-8H2;31,3-4H2,2H3;/rC21H38N2OSn/c1-4-7-17-25(18-8-5-2,19-9-6-3)21-12-10-11-20(22-21)23-13-15-24-16-14-23/h10-12H,4-9,13-19H2,1-3H3

4-[6-(tributylstannyl)-2-pyridinyl]morpholine - Physico-chemical Properties

Molecular Formula	C21H38N2OSn
Molar Mass	453.25
Boling Point	499℃
Flash Point	256℃
Vapor Presure	4.28E-10mmHg at 25°C
pKa	5.53±0.19(Predicted)

4-[6-(tributylstannyl)-2-pyridinyl]morpholine - Risk and Safety

Risk Codes

R21 - Harmful in contact with skin
R25 - Toxic if swallowed
R36/38 - Irritating to eyes and skin.
R48/23/25 -
R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.

Safety Description

S23 - Do not breathe vapour.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S29 - Do not empty into drains.
S38 - In case of insufficient ventilation, wear suitable respiratory equipment.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

4-[6-(tributylstannyl)-2-pyridinyl]morpholine - Introduction

4-[6-(tributylstannanyl)pyridin-2-yl]morpholine is an organic compound with the chemical formula C19H35N2OSn. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: colorless liquid
-Density: approx. 1.15g/cm3
-Melting point: approximately -25°C
-Boiling point: about 335°C
-Solubility: Soluble in most organic solvents

Use:
- 4-[6-(tributylstannanyl)pyridin-2-yl]morpholine is an important organometallic reagent, which is commonly used in metal-organic compound reactions in organic synthesis.
-It can be used as a catalyst and reagent for nucleophilic substitution reactions of halogenated hydrocarbons, such as amination reactions, Ullmann coupling reactions, etc.
-It can also be used to synthesize other functionalized organic compounds, such as complexes and macromolecular compounds.

Preparation Method:
The preparation of 4-[6-(tributylstannanyl)pyridin-2-yl]morpholine can be carried out by the following steps:
1. 2-chloropyridine and tributyltin chloride were reacted under alkaline conditions to obtain 6-(tributyltin)-2-pyridyl chloride.
2. 4-morpholinol is reacted with 6-(tributyltin)-2-pyridyl chloride under alkaline conditions to obtain the final product 4-[6-(tributylstannanyl)pyridin-2-yl]morpholine.

Safety Information:
- 4-[6-(tributylstannanyl)pyridin-2-yl]morpholine is irritating and corrosive and should be used to avoid contact with skin, eyes and respiratory tract.
-Need to operate in a well-ventilated place to avoid inhalation of vapors.
-When storing, keep it in a cool, dry and sealed container, away from fire and oxidizing agents.
-Wear appropriate personal protective equipment such as gloves, safety glasses and protective masks during use.

Last Update：2024-04-10 22:29:15